While you don’t reference a specific study, it wouldn’t be surprising if this was a figure that came from the CDC.
In the 1990’s, the CDC produced a bunch of studies on the costs of various diseases to society. Those costs were generally pretty low, since all they took into account were actual medical costs involved.
This started a sort of political lobbying arms race. Each major disease has an equally major foundation/association/whatever associated with it that tries to “promote awareness” or spend money on finding a cure. Each of those organizations, in turn, wants their disease to appear to worse than the others to help fundraising efforts.
So the various disease organizations started lobbying Congress to tell the CDC to produce higher numbers. Congress didn’t care, since its an entirely irrelevant issue, and over the years repeatedly told the CDC to pump up the disease cost numbers.
So the CDC progressively increased the scope of what it included in the definition of a “cost” of a disease to society. The point that we’re at now is that the CDC considers “lost happiness” to be a cost attributable to a disease. There is no definition of what constitutes lost happiness – its whatever the authors of the study want it to be – and lost happiness constitutes the vast majority of the costs that the CDC puts out.
So what you’re almost certainly seeing in the $500 billion number is a few hundred million in direct treatment costs. A few billion in lost productivity, legal expenses, administrative expenses, other social program expenditures (IE, food stamps for people who can’t work because they’re too depressed), ect… And then >$495 billion in “lost happiness.”
tl/dr: the CDC doesn’t take disease cost calculations seriously anymore. When they fund a study, they basically just tell the authors to pump the numbers as high as they think people will believe. This means that statistics you read about the cost of a disease to society are generally meaningless.
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