Every element has an atomic weight (the weighted average mass of that molecule)
If you take a Mole of atoms of one type, they have a mass of their atomic weight in grams.
Hydrogen has an atomic weight of 1.00784 u, this accounts for hydrogen, duetrerium (hydrogen-2), and tritium (hydrogen-3) present in the universe. If I have 6.28×10^23 hydrogen atoms, some of those will be deuterium, some will be tritium, but the entire volume of gas as a whole will have a mass of 1.00784 g
Hydrogen-1 has an atomic mass of 1.00783 u, so if we have a Mole of hydrogen-1, it has a mass of 1.00783 g.
If we take water (2 hydrogen and 1 oxygen), oxygen has an atomic weight of 15.999 u. 1 Mole of water molecules will weigh 15.999 g + 2*1.00784 g = 17.077 g
Avagadro’s number is simply a conversion between amu (atomic mass units) and grams
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