Mechanically? Sure, although it’d come at moderate local environmental cost due to having to dump a lot of the leftover salt *somewhere*.
The problem is the energy costs; desalination is an *extremely* energy-intensive process, such that you need an extremely powerful source of energy to drive the process. Further, water (due to it’s density) is a colossal pain in the ass to actually move any direction that isn’t downhill, thus desalination is largely only ever going to be useful in coastal areas.
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