: Could microbes develop resistance against Povidone Iodine solution? why or why not?
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Well.. yes? Microbes could develop a resistance to many chemicals and/or anti microbial substances due to random genetic mutation. This happens quite often (mutations) bc of how often microbes reproduce, however the chances of a specific mutation forming that gives it a resistance to a certain chemical is slim. However it may have already happened, but the microbe died of by some other means before it could grown into a culture. There are limits to what a microbe can develop resistances to and it would have to be a hell of a microbe to be resistant to something a strong as povidone iodine. It’s more of a “destroys everything solution” which makes small changes like mutations unlikely to result in such a massive resistance.
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