In some cases, the Giver bacterium may lose its antibiotic-resistance ability after plasmid transfer, but it depends on various factors. Plasmid transfer doesn’t guarantee permanent retention of the resistance genes in the recipient bacterium. Over time, selective pressures, changes in the environment, or other genetic mechanisms may lead to the loss of the plasmid or its resistance genes. However, in certain conditions, the resistance genes can persist, potentially contributing to the spread of antibiotic resistance in bacterial populations.
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