I can’t speak to the airplane part but, I’ve been wearing compression socks for about 3 years(I’m 40) for venous insufficiency reflux and it has made a huge difference. I am on my feet all day for work(custodian), and without the socks by the end of my shift my legs would be swollen, achy and tired, and feel heavy; not to mention the restless leg syndrome at night.
I wish I had started wearing them in my 20s when my Dr first mentioned that I could wear them for my varicose veins(just had a few at that point), but I thought they were for old people 🤷
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