Eli5, how do conservationist deal with inbreeding gene pool when trying to bring back species from being endangered?

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Eli5, how do conservationist deal with inbreeding gene pool when trying to bring back species from being endangered?

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I highly recommend “Cat Tale” by Craig Pittman. It discusses this issue really well. The story is about how conservationists are trying to save the Florida panther aka mountain lion, couger etc. from extinction.

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