Eli5: How do our digestive system recognize complex substances?

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Like, what exactly happens when you take a pill of vitamin A compared to vitamin D? Or a tiny grain of fentanyl? How exactly do our body recognize these extremely complex substances and not confuse one from another?

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It’s like those kids toys where you have to put the right shape in the hole that matches its shape. Squares go in the square hole etc. Chemicals have unique structures and properties. If I throw a bunch of triangles at the holes, the triangles will enter the triangle holes only and not the holes for the other shapes. Chemicals compounds work like this, certain molecules are too big to pass through membranes on their own or are the wrong shape to bind to certain molecules. A square can’t fit in a triangle etc.

So Vitamin D will go where it fits, Vitamin C will go where it fits, etc.

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