Eli5: How do proteins function the way they do

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I know all about transcription, protein synthesis and folding etc..
But the fact they’re too “intelligent”, this i fail to grasp.
Proteins seem to be the executive macromolecule in the body, hence they identify substances, work as enzymes, work as hormones, give signals and so on, but is their work exclusively a chemical reaction?
does it need advanced organic chemistry knowledge for me to grasp the concept?

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Anonymous 0 Comments

They work bc they’re made to do that specific thing. They’re not actually intelligent. Life has discovered that certain proteins will do these things mostly by trial and error over a couple billion years. Hemoglobin doesn’t choose to bond to oxygen, that’s just an inherent quality of hemoglobin. And animals that make hemoglobin have an advantage over animals that don’t, so the hemoglobin making gene gets passed down

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