eli5: How do small spaces run out of oxygen and why can it be deadly?

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This whole missing submarine has got me confused regarding the limited oxygen. How is it limited and what makes it deadly? How does the oxygen “run out?”

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When you breathe you consume the oxygen. You breath out carbon dioxide. In an enclosed space, there is only a limited amout of oxygen, and when this amount is converted into carbon dioxide by breathing, you suffocate

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