Eli5 How does blood know when to clot?

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When does your blood know when its the right time to form a clot?
Its supposed to happen only when blood leaves the body. If it happens in the vessels its a pretty bad idea to clot.
My first thought was it must be the contact to oxygen that triggers the clotting process. But thats nonsense since blood tranaports oxygen, right?
So how does your blood “know” its leaving the body?

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7 Answers

Anonymous 0 Comments

When blood exits the body, it will coagulate. Adding salt will keep it in liquid form. It’s not exactly an ELI5, but I learned this from butchering pigs. When I want to keep the pig blood in liquid form, I just add salt to it. If I don’t add salt to it, the blood I collect just becomes a solid clump. Later on, when I dilute the salty blood with water and bring the salt concentration down, the blood will coagulate and clump up.

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