Eli5 How does blood know when to clot?

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When does your blood know when its the right time to form a clot?
Its supposed to happen only when blood leaves the body. If it happens in the vessels its a pretty bad idea to clot.
My first thought was it must be the contact to oxygen that triggers the clotting process. But thats nonsense since blood tranaports oxygen, right?
So how does your blood “know” its leaving the body?

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Anonymous 0 Comments

It doesn’t “know” there are platelets bonding with fibrin to create a barrier forming the clot. https://youtu.be/6taZMcj8co0

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