Eli5: How does depression have physical side effects?

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Depression, which is totally abstract (as far as i understand), has physical effects like increased chances of developing Alzheimer’s and brain aging faster and in some cases physical appearance aging faster too. How?

Edit: are people thinking this question is religious or pseudo scientific? Cuz its not

In: Biology

5 Answers

Anonymous 0 Comments

I’ll admit I don’t fully understand, but I think part of the problem is the question. Depression isn’t entirely abstract. Your brain is a chemical machine, and there are chemical components to why it has problems. I’m probably oversimplifying a little bit, but depression is supposedly caused by not having enough serotonin. Maybe some forms are caused by different chemical problems, but there is to my knowledge always a physical component to the problem. Thus it’s not an entirely abstract problem, and there’s no reason why the consequences of it should all be abstract.

Think of it this way, your brain is an engine, and serotonin is like motor oil. Your engine needs a certain amount of motor oil to run properly, and consistently not having enough of it will put stress on your engine. In much the same way, your Brain needs a certain amount of serotonin to function properly. As for premature aging, stress on the brain is stress on the body, and stress causes premature aging.

Keep in mind I’m not a doctor. Just someone diagnosed with depression that has a limited understanding of it. I’d be interested to hear a more educated perspective because I’d really hate to spread any misinformation.

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