ELi5: How does DNA tests identify a person if that persons DNA is in no database?

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Say a crime has been committed, and the police find either blood or semen at the crime scene. However, the perpetrator has committed no prior crimes and therefore his DNA is in no database or registry. How are analyst able to find out who the perpetrator is through analyzing either the blood or semen found at the scene?

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Anonymous 0 Comments

DNA evidence isn’t used that way. They don’t just find the culprit from the DNA found at a scene.

Instead DNA evidence would typically used to corroborate other evidence against someone who is already a suspect. Like someone would be found to have a motive to kill the victim, be spotted in the area the victim was found, the murder weapon being found in their car, *and* their DNA evidence being found at the scene. Under such circumstances the investigators already know who they think did it and can just compare their DNA, they aren’t just finding DNA and using it to identify the culprit from the population at large. In concept it might be possible to get general features like the DNA being from a male, Caucasian, with brown hair, but not much more than that.

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