Eli5: How does Saline Solution work within the blood stream?

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Fellows,

I’m reading about donating blood, and they said that in large volume plasma donation, a replacement of saline is added to your blood stream to account for the large volume taken. I’m just wondering how it’s okay to just replace blood with Saline

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https://en.wikipedia.org/wiki/Saline_(medicine)

https://www.utmb.edu/pedi_ed/corev2/fluids/Fluids6.html

As opposed to water?

Your body is made of cells that are mostly water with stuff in them. The cell membrane is semipermeable, so water can move back and forth as needed: https://www.khanacademy.org/science/ap-biology/cell-structure-and-function/mechanisms-of-transport-tonicity-and-osmoregulation/v/osmosis Replacing your blood with just water doesn’t have enough stuff, so water will rush into your cells. This is not good.

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