When two or more atoms combine into a stable molecule, they become –well, combined. Their shape becomes more complex and larger. Their components are now sharing electrons which shifts around their magnetic/electrical charges on the structure. So, naturally, these new larger molecules are going to interact with the things around them very differently than their smaller components would. Think of it like chemical puzzle pieces, or housekeys, where even slight differences in shape or size can radically change an item’s functioning.
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