eli5: If fever is our body’s response to kill an infection, then why do we take medicines like paracetamol that control the fever?

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Also, I get that the fever can get really high at some point, which causes other effects, but why is our body not able to control its response to the infection so as to not do more harm with the fever?

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Anonymous 0 Comments

Our biological systems aren’t perfect, not by a long shot. They respond well in certain situations, but they can’t possibly react appropriately in all situations. Evolution is far too slow for these systems to keep up with every change.

There will be circumstances where an immune reaction is not desirable and causes damage. The only thing that matters to evolution is that enough individuals of a species survive to propagate the species. A few dying in extreme situations won’t necessarily prompt adaptations.

A lot of the time, it’s about the lesser of two evils. It’s better to risk complications due to a fever that’s too high, than not respond aggressively to a virus.

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