It is possible for your blood pressure to essentially be negative for brief periods of time (at least somewhat locally) and have something that is not blood (usually air) enter your blood.
The brief version is that the same process that causes air to enter your lungs doesn’t really care how it gets there. If you have an opening to your larger blood vessels from either trauma or more commonly a central line (think big IV) in your neck/abdomen, it’s possible to have air enter your blood and give you a bad time.
Look up “air embolism”.
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