eli5: If your leg gets amputated, how does your body know to not produce enough blood to replace what was lost?
In: 2195
To put it simply: The production of blood, specifically RBC, is triggered by the availability of oxygen. No problem in oxygen availability? Then, the body will only produce enough “RBC maker.”
“RBC maker” is an erythropoietin which triggers the bone marrow to produce RBC.
When it comes to plasma, which consists mostly of water, the brain senses if we need more water or not. If we don’t need water to create plasma, then no need to do so.
In summary, our bodies have indications if we need something or not. Since, after amputation, our body is still a closed system, hence, our organs live in harmony.
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