eli5: If your leg gets amputated, how does your body know to not produce enough blood to replace what was lost?

Question

eli5: If your leg gets amputated, how does your body know to not produce enough blood to replace what was lost?

In: 2195

Answer 1

>If your leg gets amputated, how does your body know to not produce enough blood to replace what was lost?

If you lose a leg, you also lose the long, marrow filled bones in which the blood is produced. A missing limb means less need for blood and less capacity to produce blood, so it balances out.