eli5 Is the immunity different in people with schizophrenic and Parkinson people receiving dopamine manipulating meds ? What is the relation with dopamine antagonist and agonist with immunity to diseases, cancers etc ?

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eli5 Is the immunity different in people with schizophrenic and Parkinson people receiving dopamine manipulating meds ? What is the relation with dopamine antagonist and agonist with immunity to diseases, cancers etc ?

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Anonymous 0 Comments

Schizophrenia and Parkinson’s are completely different disorders. Antipsychotic medications prescribed for schizophrenia can cause “Parkinsonian” side effects that resemble Parkinson’s, but are still unrelated. Because schizophrenia can interfere with a person’s ability to take care of themselves, schizophrenics are more likely to have weaker immune systems, and treatment with antipsychotics can exacerbate this in some cases.
The term is “Dopamine *agonist*” not antagonist. These medications block dopamine by making the brain think it’s made enough, and are used to reduce involuntary motor agitation (Parkinson’s, restless leg syndrome).
Dopamine agonists do not make a person immune to disease, and there is nothing that will make a person immune to cancer.

Anonymous 0 Comments

There are too many unknowns here to give complete and conclusive answers to these questions. Dopaminergic signaling in immunology is an [active research topic](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832385/) and many knowledge gaps remain.

Also, looking at your post history asking for studies and concrete data, you may want to be asking over at r/askscience instead. It would probably also help if you organized your questions and find a common thread instead of posting lots of separate questions.