Eli5: researching amphetamines and methylphenidates mentions isomers frequently, I don’t get the biochemistry of it

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Don’t even know what isomers do in the body. I’m trying to find a stimulant that will work well with my brain, it tells me a lot about how my brain works when I can tolerate vyvanse over adderall. I’ve researched on every single stimulant available & they essentially all work on dopamine, seratonin & the other one lmao. I know some have just dextro & then dextro and levo, I get the chemistry of it but how the chemistry works in the brain is confusing me, I get that some tell dopamine to keep producing & some overflow dopamine, I just don’t get what isomers & the many other things it’s doing. I want to know every single detail of what they’re doing to my body and why. I want to find the most effective one for me & know how to keep myself healthy based on what it effects.

Note: I see a psychiatrist but she is not going to teach me chemistry so this is for my own awareness. It is also fascinating. Even if I were to take medical advice, a medical professional would have to approve it so I don’t get those comments.

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Anonymous 0 Comments

The simple picture they use in pharmacology textbooks is that of a key (chemical of a certain shape and electronic configuration) in a lock (receptor on a synaptic cleft or cell membrane of a neuron)

>I get the chemistry of it but how the chemistry works in the brain is confusing me,

So the chemistry/physical shape of right handed or left handed (3D chemical orientation) around a carbon atom with 4 single bonds happens at every carbon atom with 4 single bonds.

In the case of Adderall

>The mixture is composed of equal parts racemic amphetamine and **dextroamphetamine**, which produces a (3:1) ratio between dextroamphetamine and **levoamphetamine**, the two enantiomers of amphetamine. Both enantiomers are stimulants, but differ enough to give Adderall an effects profile distinct from those of racemic amphetamine or dextroamphetamine

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