Eli5: Since Mitochondria play an important role in cancer through macromolecular synthesis and energy production, why are we not targeting those energy path ways to exhaust cancer?

Question

Eli5: Since Mitochondria play an important role in cancer through macromolecular synthesis and energy production, why are we not targeting those energy path ways to exhaust cancer?

In: 3

Answer 1

What role does the mitochondria play in cellular macromolecule synthesis? Unless we are calling NTPs macromolecule then I’m unfamiliar with any that the mitochondria produce. Usually macromolecule means a biopolymer, like a peptide chain, saccharide chain, a a glucoseaccharide, DNA/RNA, etc.

Unless you are talking about mtDNA and the associated replication proteins, I haven’t been taught too much about those or where those originate within the cell