eli5 transdermal absorption

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I read that magnesium can be absorbed thru skin and enter the bloodstream but I’m struggling to visualize where it all goes.

Does it actually matter if you apply it to the affected area? Is a partial “spot treatment” possible or do they distribute equally at a constant rate?

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Transdermal absorption is when substances can go through your skin and get into your bloodstream. The skin is like a protective barrier around your body, but some things can pass through it.

One example of this is magnesium. Magnesium is a mineral that your body needs to work properly. Sometimes, people use special products like magnesium oils or lotions that you put on your skin. When you apply these products, the magnesium can go through the outer layer of your skin and reach the parts underneath.

Once the magnesium gets through your skin, it can enter your bloodstream and travel all around your body. This is helpful because magnesium is important for lots of things in your body, like your muscles, nerves, and making energy.

When you apply the magnesium to a specific area, like if you have a sore muscle, some of it will stay in that area and may help make it feel better. But a good amount of the magnesium will also go into your bloodstream and reach other parts of your body.

So, when you use transdermal magnesium, it can have both local effects on the area where you put it and systemic effects on your whole body. The exact amounts and effects can be different for each person, but that’s the general idea.