Eli5 What are the long term consequences of drugs that suppress REM sleep?

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It’s well known that drugs such as antidepressants (particularly SSRIs) and benzodiazepines suppress REM sleep,it’s also well known that REM sleep is crucial for memory,cognition,consolidation of memory and many other important functions,my question is what are the long term outcomes of drugs that suppress REM?

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13 Answers

Anonymous 0 Comments

Wait, you guys actually sleep the first 1-2 weeks of cutting out weed? I literally stay up for more than 5,6…7 days straight or even longer. And I never smoke more than a couple bowls of flower a day

Anonymous 0 Comments

Michael Jackson was given Propofol to induce sleep. It was administered intravenously by his personal physican. No REM sleep occurs when Propofol is used. He was given this drug every night for several weeks as he was preparing for a world tour that would never happen. Those around him noticed his troubling decline during this time. He wasn’t able to remember song lyrics or dance moves. He exhibited symptoms of dementia. For Michael Jackson the consequence of a drug that suppressed REM sleep was death.

Anonymous 0 Comments

My experience: I’ve used antidepressants, cannabis and alcohol for my sleeping problems.
Worst was alcohol. Made me see weird dreams, restless nights and pink elephants. Sometimes right before falling asleep I would stop breathing or wake up in terror (same sober when in a higly anxious state)
Then comes sleepingpills/antidepressants I slept yes, but no REM, well sometimes nightmares, most of the time I’d just wake up feeling anxious, tired and physically ill.
Cannabis has helped me to get sleep, fall asleep and stay asleep. I don’t remember dreams everynight but I know I’ve dreamt. I wake up waaaaay more rested after hitting gravitybong than taking pharmacy-drugs.

Could different people have different reaction to these? Maybe some needs a lower doze on THC to sleep better and others a little heavier on benzos?

Edit: and my memory is pretty much the same.