All living things have DNA. In humans and other animals this DNA is arranged in chromosomes. The chromosomes have caps on the ends that protects them called telomeres. Every time a new cell is made oh, the telomeres get shorter. As the telomere has run out, you see the signs of aging. At some point the organs become inefficient and the body eventually shuts down.
The faster a speices cells divide, the longevity of their organ tissue, the efficiency of their kidneys and liver, and their diet and lifestyle all factor into age.
Human tissue is pretty long lasting compared to most species, as cells divide DNA is slowly broken down, until cancer or organ failure or a dozen other diseases set in.
Longevity might be partly decided by natural selection… A creature with a certain combination of anatomical/physiological features and behaviors living in a certain habitat will die eventually from causes not related to aging, such as predation, accidents, diseases, even if it could otherwise theoretically never die of old age. And so the genetic code of that species simply isn’t “built” to function very long past the average amount of time that the creature would normally live. This is also related to the span of the creature’s reproductive life.
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