eli5 What happens biologically when we become accustomed to spicy food?

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My wife can swear that her mouth is on fire after eating certain foods, but when I try the same exact food I often barely detect the heat she’s talking about.
I wasn’t always like this, it was an acquired taste. Sweet chilli used to be hot to me, now I dabble with habanero, naga, etc so I know something has changed physiologically…what was it?

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Anonymous 0 Comments

One thing I haven’t seen mentioned is that everyone has a different tolerance to capsaicin. Separate from pain tolerance, everyone reacts to capsaicin differently. So people that don’t feel the heat as much aren’t actually tougher necessarily, they could just have receptors that don’t react as strongly.

A lot of people like to act like they are tougher than others if they can eat spicier food, but it’s not necessarily a matter of toughness.

But maybe your wife is just a weakling that can’t handle pain and you’re a tough manly man with much higher pain tolerance.

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