THC alters the area of the brain that is responsible for feeling full. The hormone which makes us feel full is called Leptin
So when THC interacts with natural cannabinoids present in that area, the switch happens and Leptin stops getting released, so you stop feeling full and the feeling of not eating goes away and then within an hour max, the area starts producing another hormone that causes us to feel hungry called ghrelin, so less leptin and more ghrelin leads to munchies
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