Eli5 What is ‘binding’ in neuroscience’?

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Tourette’s Sufferer here… I read a publication that stated ‘Serotonin binding is increased in Tourette’s disorder’… I’ve read and re-read the article and tried learning about ‘binding’ but cannot understand what it means in that article… does it mean Tourette’s patients have more Serotonin flying around or less Serotonin… what is binding?

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