eli5: What is Excema doing from a cellular level?

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Is it a corruption in the skin cells? What exactly is happening?

In: Biology

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Eczema causes the immune system to react, sometime to an external irritant. The immune system, it turn, causes inflammation in an attempt to “Remove” what it sees as a foreign irritant. This inflammation causes the dry and flaky skin associated with eczema. In some cases, fluid-filled blisters also form in an attempt to repair the damage of remove the foreign object.

If you get a cut on your hand, you’ll see that it gets red and feels warm and sometimes weeps fluid. This is the same thing eczema does, but without the cut. This is the result of an over-active immune system, though nobody is 100% sure what causes it.