eli5: What is the difference between anti depressants, anti psychotics, and mood stabilizers?

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and why would someone move from one to the other?

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2 Answers

Anonymous 0 Comments

All three of these medications are through to primarily regulate different neurotransmitters.

Antidepressants are thought to regulate serotonin; that is, they increase the levels. This is usually used for depression spectrum disorders which can range from things like premenstrual dysphoric disorder to of course, major depression.

Antipsychotic are thought to regulate dopamine; they decrease dopamine. These drugs are used to treat psychotic disorder which can include things like schizophrenia or even manic bipolar disorders.

Mood stabilizers are a bit different, their mechanism isn’t as well understood. There are 2 main drugs, lithium and valproate. Lithium is thought to increase inhibition and decrease excitation in the brain. Valproate is also thought to decrease excitation.

What’s important, is that there’s a lot of very complicated interplay between all of these neurotransmitters and how they interact/cause psychiatric symptoms. Also, these drugs can often be used for other purposes including symptoms in dementia, appetite loss, etc. There’s also a lot we don’t know and we’re constantly learning new things everyday!

TLDR; antidepressants = depression, antipsychotics= schizophrenia, mood stabilizers = bipolar

Anonymous 0 Comments

These are classified as distinct types of medicine because they target specific parts of the brain in the own unique way. The reason one moves thru these would be because… from my experience… they are attempting to attack different problems as they evaluate you and your bodies response to the medicine. If the anti-depressant aren’t working, they try a different anti-depressant. If they just don’t work.. then the depression is a symptom… of something worse.