eli5: What is the original purpose of cannabinoid receptors in the human body?

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Why did the human body develop the ability to engage with cannabinoids? I’ve heard people postulating that we’re practically build to get high, as a justification for cannabis usage, but I can’t really believe it would be the main cause for this specific natural selection. I mean; from a darwinian perspective it doesn’t really make sense – how would getting high be survival of the fittest? Also, there exist other cannabinoids than THC, so what is the effect of these, and how present are they in our daily lives and what are the effect of these?

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Anonymous 0 Comments

Yeah, imagine the receptors being like the child’s toy where you have to match an object to a hole that’s the same shape as the object.
The fact that cannabinoid receptors are called what they are is that it was found out that the cannabinoid fits their “shape”.

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