Why did the human body develop the ability to engage with cannabinoids? I’ve heard people postulating that we’re practically build to get high, as a justification for cannabis usage, but I can’t really believe it would be the main cause for this specific natural selection. I mean; from a darwinian perspective it doesn’t really make sense – how would getting high be survival of the fittest? Also, there exist other cannabinoids than THC, so what is the effect of these, and how present are they in our daily lives and what are the effect of these?
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Human cells, neurons, receptors, etc. can be considered like a “puzzle piece” or a “lock”.
Chemical compounds can be considered like another “puzzle piece” or a “key”.
If you make one random lock and one random key, the odds are very low that the key will match the lock.
If you make *very many* random locks and *very many* random keys, you’ll probably eventually find some keys that happen to match some locks.
Some of those random matches are then selected for (evolutionary pressure), but not all of them; some of them just happen to exist because of chance and the very large numbers involved (consider how many plants there are, and how many compounds they all make; it would be surprising if *nothing* in the plant ecosystem happened to interact with our biology, even without any evolutionary pressure at all.)
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