People who get sent to space are in excellent physical condition. The likelihood that they suffer from a heart attack or something else like that is very low.
They also have some level of medical training before going up. They’re obviously not as trained as a full doctor, but they’re above a typical First Aid class. They also have doctors on staff on the ground who not only monitor the astronauts remotely but are also able to guide them through an emergency event.
There’s also special training for stuff like CPR in space, where being in zero G affects how it is done compared to on Earth.
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