Eli5: When humans get too fat or obese there is a high risk of heart related issues. But in nature for example Walrus is or hippos are so fat in shape almost their body is consists of fat and are they same sick like humans?
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The causality works the other way.
When humans get insulin resistant, there are metabolic changes – higher triglycerides, lower, HDL, higher blood glucose – that lead to a higher risk of cardio vascular disease. And higher risk of type II diabetes.
Those changes also lead to weight accumulation in most people, though some people can be metabolically sick and still be thin.
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