Eli5: When we sleep, spinal fluid washes waste from our brain. What exactly is “waste” in the brain?

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Eli5: When we sleep, spinal fluid washes waste from our brain. What exactly is “waste” in the brain?

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Side note: Adenosine builds up while we sleep. It is responsible for the “sleepy” feeling we have when we wake up. It is in a dance with melatonin and light creating our circadian rythm. You can manipulate the production by exposing yourself to light, cold, coffee, and exercise.

In other words, you can move your adenosine cycle around by exposing yourself to one minute cold shower, then 10 minutes of sunlight, and twenty minutes of exercise. This is how you can get accustomed to waking up at 5AM if needed. Keep in mind you will need to go to sleep earlier. There is a similar set of things you can do in the evening to help adjust that side of circadian rhythm as well.

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