[ELI5] Why are medications dispensed at very specific/seemingly almost spontaneous solution/dosage amounts?

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I am sure there is a reason why. But, I have always wondered if a slight variation would change things.

For example. A bag of sodium chloride 0.9% is commonly dispensed at hospitals and clinics. Why is it *specifically* 0.9%? Would there be a completely different effect if it were, say, 0.10%? Or 0.85%? Or did people just realize this amount happened to work and it became default?

I also have seen medications of random components that will be like *insert chemical* 0.15% or a medication like colchicine at 0.6 MG. Why isn’t it 0.5 MG??

Just curious. Hopefully not a stupid question.

In: Chemistry

3 Answers

Anonymous 0 Comments

The testing and research showed what the effective doses are. The data shows what doesn’t have the intended effect and the dosage at which no more positive effect can be had (or where it gets toxic). With saline solutions, for example, salt is one of those things that we die from too little of and die from too much, so the amount used has to be within the healthy zone for the body.

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