The brain is too complex and too poorly understood for us to (currently) treat psychiatric problems directly from our understanding of the brain in most cases. It’s like of like predicting the weather – yeah, in principle you could track every particle of gas in the air everywhere, but in practice you rely on general trends like “there’s a cold front”. The two fields do overlap, but one deals more with the underlying theory and the other with the clinical practice, and that clinical practice isn’t always based on theory so much as “we tried this thing and it worked”.
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