eli5: why are some medicine’s absorption affected by food?

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I understand that certain food’s acidity can affect absorption and other substances in food can interfere with liver enzymes… are these the two most common factors?

In: Biology

3 Answers

Anonymous 0 Comments

It’s different from one to the other, but a lot of it is because of binding. Some meds “stick” to calcium, so drinking milk makes less of the med free for your body to use. Sometimes it’s something in food that binds to the same protein that metabolizes the drug, so more of the drug stays in your system, making it more potent and potentially toxic.

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