Metabolism differences. Spiders for instance have a metabolism speed 50% less than any other creature their size. They also have a low effort lifestyle with minimal movement compared to busy humans, so they don’t burn nearly as much energy, and so don’t need to replace it often. The same applies to water, which they get from their food and do not drink as we humans do. They are so sedentary and their metabolism so slow, that some can go two years without food.
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