[ELI5] Why can we gain resistances to medicine, alcohol, poison, etc. but not so much for allergies or pollutants?

Question

[ELI5] Why can we gain resistances to medicine, alcohol, poison, etc. but not so much for allergies or pollutants?

In: 1276

Answer 1

With severe allergies, and I hope someone corrects me cause I’m not 100% sure on this, each reaction gets increasingly severe. Like the opposite of building a resistance, each time a reaction occurs subsequent reactions will most likely be worse.