[ELI5] Why can we gain resistances to medicine, alcohol, poison, etc. but not so much for allergies or pollutants?

Question

[ELI5] Why can we gain resistances to medicine, alcohol, poison, etc. but not so much for allergies or pollutants?

In: 1276

Answer 1

We can, we just have to do it over a long time. Starting off with very small doses and working our way up like people who drink a lot do, or people on opiates do. It’s more of a thing of titration (that starting small and moving up), consistent doses and all that.

In fact there’s this girl on tiktok (link [here)](https://vm.tiktok.com/ZML3xnTWV/) that ate a small piece of carrot every day, slowly increasing the amount snd she slowly became less and less allergic.

But in situations where allergens cause a large reaction like anaphylaxis, the potential damage to the body (death, serious injury and bodily damage) out way the positives of being able to eat/be in contact with your allergen.