Eli5 why can’t we continuously take caffeine and never sleep?

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I work overnight shifts (11pm-7am) and take caffeine pills to stay awake. When I get home, even if I take more caffeine I’m sometimes still too tired and fall asleep. Why does it eventually stop working? Is there some sort of chemical limit? Why can’t caffeine replace sleep for longer periods of time (like days on end)?

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Anonymous 0 Comments

This isn’t really an answer to your question, but just some examples of what happens to a body when extremely sleep deprived. When I was in architecture school, people would often live off maybe 8 hours of sleep. For the whole week. And then pull two all-nighters in a row. And that was usually preceded by weeks of significant sleep deprivation as well. By the end of it, we would look and feel so disgusting. Our skin would be mottled. Our faces would look like they had been deflated. People would sometimes randomly vomit. We’d have gastrointestinal problems, body tremors, heart palpitations. My body would have a hard time regulating my body temperature. We had to make models during this time and many would have accidents, like pushing their fingers into bandsaws and sanding their whole fingernails off with belt sanders. It was a truly horrible culture. If you’re motivated enough, you can stay up for long periods of time, even to the point where you’re breaking your body down. I somehow did it without caffeine, but most of my classmates drank it. I know you’re just asking out of curiosity, but our bodies need sleep to function properly. If they don’t get it for prolonged periods, everything starts to go downhill. No one is missing out on any extra life by getting good sleep. Good sleep makes all your waking hours better.

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