Eli5 Why can’t we just make a medication that tricks your body into burning energy without you actually moving?

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Like I get that it could be dangerous and the process is complicated but we can make medications that trigger/inhibit all sorts of biological functions why are weight loss pills that are scientifically engineered to work not a thing yet?

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Anonymous 0 Comments

There is a chemical that does just this. It is called DNP. It is very dangerous and banned, at least in the USA.

It works by blocking one of the last energy production steps in your body: preventing production of ATP. All that extra energy turns into heat instead. It is like if you put your car in neutral and just press the gas petal all the way down. You’ll use up a lot of fuel and blow up your engine.

The side effects are mostly over heating, but also cellular hyperthermia or your individual cells overheat and die. There are also some other toxicities that are still being researched. It is very hard to keep a safe dosage.

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