eLI5 Why do certain painkillers work for certain things and others not

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For example, I had mild toothache on and off since July and paracetamol pretty much did nothing. I may as well have been eating smarties, then I had the offending tooth out and the bruising on my jaw from the injections has been much more painful but paracetamol stops the pain within 15 mins. Why didn’t it work for the much milder toothache?

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Anonymous 0 Comments

I’m terrified of dying because I imagine it being more painful than a toothache. I got one on a Friday night one time and had to go all weekend. I gargled tequila all weekend and I don’t remember it helping. My friend told me to get some cocaine and rub it on my gums. I didn’t know any cocaine dealers.

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