I’m surprised nobody is mentioning [Kindling](https://en.wikipedia.org/wiki/Kindling_(sedative%E2%80%93hypnotic_withdrawal)). Alcohol hangovers can be seen partly as manifestations of acute alcohol withdrawal. Over time, the CNS becomes more and more sensitive to these withdrawal states and consequently your hangovers get worse and longer.
As you age your liver becomes less effective at producing the enzymes necessary to metabolize alcohol and remove those metabolites from your body. As others have posted, alcohol creates a lot of oxidative stress on the body; particularly in the brain and cardiovascular system. This means while your liver is taking longer to remove the alcohol, the alcohol and it’s metabolites (some which are even more destructive than ethyl alcohol itself) have more time to hang out in the body and do harm on a cellular level.
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