Eli5 Why do some drugs (ie party drugs) work immediately while others need time (weeks) to get in your system? Could a higher dose get them in your system faster?

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Eli5 Why do some drugs (ie party drugs) work immediately while others need time (weeks) to get in your system? Could a higher dose get them in your system faster?

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Anonymous 0 Comments

Some of them are harder to sintesize thus making it “slow effect”, like if u start eating a piece of meat that’s tender vs one that is tough.

Anonymous 0 Comments

Higher dose doesn’t get in the system faster it’s just noticeable earlier because the effects (even minor ones in a come up) are stronger

Anonymous 0 Comments

Some of them are harder to sintesize thus making it “slow effect”, like if u start eating a piece of meat that’s tender vs one that is tough.

Anonymous 0 Comments

Higher dose doesn’t get in the system faster it’s just noticeable earlier because the effects (even minor ones in a come up) are stronger

Anonymous 0 Comments

Some of them are harder to sintesize thus making it “slow effect”, like if u start eating a piece of meat that’s tender vs one that is tough.

Anonymous 0 Comments

Higher dose doesn’t get in the system faster it’s just noticeable earlier because the effects (even minor ones in a come up) are stronger

Anonymous 0 Comments

Party drugs work quickly because if they didn’t work quickly it wouldn’t be much of a party. Kind of a contextual self-selection thing happening there.

Imagine if you did a line of blow and then had to wait a week. That’s no fun.

Anonymous 0 Comments

Party drugs work quickly because if they didn’t work quickly it wouldn’t be much of a party. Kind of a contextual self-selection thing happening there.

Imagine if you did a line of blow and then had to wait a week. That’s no fun.

Anonymous 0 Comments

Party drugs are usually going after easily accessible targets and you generally accept the side effects.

Long, slow acting drugs like antidepressants are going after much harder (more complex) symptoms and trying to minimize side effects. It’s a harder, slower job.

It’s also true that party drugs are just better drugs from the efficacy point of view, and usually worse from the side effects and safety points of view. Fentanyl is an amazingly good painkiller, hugely better at killing pain than ibuprofen. But fentanyl kills you if you overdose a narrow therapeutic range and ibuprofen doesn’t, so the latter is in common use.

Antibiotics are best of both worlds. They are usually fast acting on bacterial targets and have no mammalian targets so you get fast and high efficacy!

Anonymous 0 Comments

Party drugs are usually going after easily accessible targets and you generally accept the side effects.

Long, slow acting drugs like antidepressants are going after much harder (more complex) symptoms and trying to minimize side effects. It’s a harder, slower job.

It’s also true that party drugs are just better drugs from the efficacy point of view, and usually worse from the side effects and safety points of view. Fentanyl is an amazingly good painkiller, hugely better at killing pain than ibuprofen. But fentanyl kills you if you overdose a narrow therapeutic range and ibuprofen doesn’t, so the latter is in common use.

Antibiotics are best of both worlds. They are usually fast acting on bacterial targets and have no mammalian targets so you get fast and high efficacy!