eli5 Why do we get a red bump when bitten by an insect?

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eli5 Why do we get a red bump when bitten by an insect?

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Cells that are damaged either physically by the bite or chemically by the insect’s saliva release chemicals of their own that cause inflammation. Inflammation is the general term used to represent the body’s response to invasion. The area becomes red because tiny blood vessels enlarge to increase blood flow to the area (provides nutrients to cells and helps immune system cells get there to fight germs). It becomes swollen because those blood vessels become leaky (helps immune system cells get through). It itches/is painful to let your brain know “hey there’s something wrong over here, please address this”.

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