Eli5 – why do you take antibiotics as a course and not all at once?

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I’ve just started an antibiotics course which is 4 times a day for 10 days and that got me wondering if they would be just as effective if I took them all and why not.

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Anonymous 0 Comments

RN here: Most antibiotics are actually quite toxic to humans above a certain dose and with several serious side effects even when taken too closely together. If you took even one extra dose in a day for example you could be puking your guts out, having seizures, getting kidney damage, liver damage etc.

There are other reasons to spread out antibiotic therapy over several days or even weeks to months. But there are very very few infections that could be eradicated in a single day, even if the antibiotics didn’t kill you. The other huge factor here is that bacteria are living cells and it can take time for your immune system to clean up the mess. You don’t necessarily want every single bacteria dying simultaneously.

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