Eli5 – why do you take antibiotics as a course and not all at once?

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I’ve just started an antibiotics course which is 4 times a day for 10 days and that got me wondering if they would be just as effective if I took them all and why not.

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Anonymous 0 Comments

A couple of things are happening here, first is that when you put something into your body, it either breaks it down into parts to build cells, or it gets rid of it (at least it tries to).
The other is that to completely kill off the bacteria, they need to be exposed to the drugs for a prolonged period of time.

If you took all the antibiotics at once, one of two things would happen: One possibility is that the drugs spend a very brief time in your system before they get flushed out, so the bacteria would only be exposed to a very high dose briefly, which might kill more of them at first but still leave a bunch to continue growing the infection. The other possibility is that such a high dose of antibiotics would overwhelm the systems in your body that take care of “getting rid of stuff” like the kidneys and liver and damage them. Neither option is good for you.

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